Cholesteryl homosuccinate
WebJul 1, 1994 · In the present study we have established that the antitumor activity of alpha-tocopheryl succinate (TS, vitamin E succinate) and cholesteryl succinate (CS) result … WebMar 9, 2007 · Cholesterol hemisuccinate (compound 5), which consists of succinic acid esterified to the beta-hydroxyl group of cholesterol, selectively and strongly inhibited the activities of mammalian DNA polymerases (pols) such as pol beta, pol lambda, and terminal deoxynucleotidyltransferase (TdT), which are family X pols, in vitro, and the IC50 values …
Cholesteryl homosuccinate
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Webpurification, we have developed a protocol to solubilize 2% w/v cholesteryl hemisuccinate in 10% w/v detergent stock solutions. The protocol consists of two main stages: … WebCholesteryl hemisuccinate is an ionizable anionic detergent that stabilizes large unilamellar vesicles. These liposome vesicles act as delivery agents for anticancer …
WebThis web site. PDBj; Yorodumi; PDB-7xbd; Cross-search: WebJul 1, 1994 · In the present study we have established that the antitumor activity of alpha-tocopheryl succinate (TS, vitamin E succinate) and cholesteryl succinate (CS) result from the action of the intact TS and CS compounds and not from the release of alpha-tocopherol, cholesterol, or succinate. We report that …
WebProduct Description. Cholesteryl hemisuccinate is a cholesterol ester with anticancer activity. 1 It inhibits the growth of murine C1498 myeloid and L1210 lymphocytic … WebCholesteryl hemisuccinate is a dicarboxylic acid monoester resulting from the formal condensation of the hydroxy group of cholesterol with one of the carboxy groups of succinic acid. A detergent that is often …
WebFeb 1, 2003 · We have now studied the effect of cholesteryl-hemisuccinate (CS) on the fate of HL-60 cells to clarify whether CS has an effect similar to that of VES. CS inhibited the growth of HL-60 cells without differentiation to granulocytes and induced DNA fragmentation and ladder formation.
WebFeb 1, 2000 · Cholesteryl hemisuccinate (CHEMS) is a good acid-environment-responsive material; it is composed of succinic acid and cholesterol β-alcohol based on esterification [13]. The many acid-sensitive ... navy nwu type 3 authorized bootsWebC326 Cholesteryl Hemisuccinate Tris Salt Chs Anatrace, supplied by Anatrace, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more marks and spencer french cheese selectionWebAim: To study the membrane stabilization effect and mechanism of cholesteryl hemisuccinate (CHEMS) on dipalmitoylphosphatidylcholine (DPPC) liposomes; … navy o-5 line active dutyWebNov 21, 2024 · Among the various cell membrane components, cholesterol (CHL) is known to regulate protein function and its concentration can reach up to 50 mol %. However, … navy nwu type iii coyote fleeceWebCholesteryl Hemisuccinate is not a Good Replacement for Cholesterol in Lipid Nanodiscs The Journal of Physical Chemistry B. Nanodiscs are suitable tool for studies of … marks and spencer frozenWebAug 26, 2005 · In the present study, cholesteryl hemisuccinate (CHEMS) was evaluated for use as a membrane stabilizer in dipalmitoylphosphatidylcholine (DPPC) liposomes. … marks and spencer framed printsWebThen, a solution of the appropriate homosuccinate (44 μ mol) and triethylamine (175 μ mol) in anhydrous ACN (0.5 mL) was prepared. The solution was added to the support, and then a solution of 2- (1 H -benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate (TBTU) (175 μ mol) in anhydrous ACN (300 μ L) was added. marks and spencer fosse park opening hours