Chemokine ligand 2
WebMar 9, 2024 · Chemokines and chemokine receptors play a critical role in RA pathogenesis via immune cells recruitment. Several chemokines and chemokine receptors are abundant in the peripheral blood and in the local inflamed joints of RA. Furthermore, synthetic and biologics disease modifying anti rheumatic drugs have been reported to affect … WebMar 9, 2024 · These immunostimulatory molecules include (but most likely are not limited to): ATP,149 150 cellular nucleic acids,151 152 the non-histone, nuclear DNA-binding protein high mobility group box 1 (HMGB1),153–156 the member of the annexin superfamily annexin A1 (ANXA1),157 cytokines like type I interferon (IFN), C-C motif chemokine …
Chemokine ligand 2
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WebCCL2 Antibodies. (Chemokine (C-C Motif) Ligand 2 (CCL2)) This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. WebAug 31, 2024 · CC chemokine ligand-2 (CCL2), a proinflammatory chemokine that mediates chemotaxis of multiple immune cells, plays a crucial role in the tumor …
WebThis antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided … WebDec 29, 2006 · The members of the human and mouse chemokine superfamily are listed in Table 1, together with their receptors, and shown in schematic form in Figure 1; phylogenetic trees for the two superfamilies are shown in Figure 2.The two main chemokine ligand superfamiles are named according to the arrangement of the (typically four) cytokines …
WebCXCL10. C-X-C motif chemokine ligand 10 (CXCL10) also known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10 is an 8.7 kDa protein that in humans is encoded by the CXCL10 gene. [5] [6] C-X-C motif chemokine 10 is a small cytokine belonging to the CXC chemokine family. WebCytokine Panel, Plasma or CSF DNTC Sort EBV Immortalization Ektacytometry, Osmotic Gradient F Cell Analysis, RBC – by flow cytometry Foxp3 Glucose-6-Phosphate Dehydrogenase (G-6-PD) Testing GM-CSF Autoantibody (GMAb) GM-CSF Receptor Stimulation Assay Heinz Body Preparation Hemoglobin A1c Hemoglobin Electrophoresis …
WebCCL2 ELISA Kits. The ELISA kits listed below target CCL2, the symbol for the human gene, C-C motif chemokine ligand 2, and a member of the Intercrine beta (chemokine CC) family. The protein encoded by CCL2 has a predicted amino acid length of 99, a mass of 11 kDa, and a secreted subcellular localization. Glycosylation has been reported.
WebMar 21, 2024 · CCL2 (C-C Motif Chemokine Ligand 2) is a Protein Coding gene. Diseases associated with CCL2 include Neural Tube Defects and Human Immunodeficiency Virus … dakine 365 pack 30l rugzakWebchemokine (C-C motif) ligand 12. Synonyms. MCP-5, Scya12 Feature Type. protein coding gene. IDs. MGI:108224 NCBI Gene: 20293. Alliance. gene page. Transcription Start Sites. 2 TSS. Location & Maps more. Sequence Map Chr11:81992671-81994225 bp, + strand. From NCBI annotation of GRCm39 ... doctrine\u0027s zgFor the ICAO airport code see Candle Lake Airpark, for the diradical compound see Dichlorocarbene. The chemokine (C-C motif) ligand 2 (CCL2) is also referred to as monocyte chemoattractant protein 1 (MCP1) and small inducible cytokine A2. CCL2 is a small cytokine that belongs to the CC chemokine family. … See more In the human genome, CCL2 and many other CC chemokines are located on chromosome 17 (17q11.2-q21.1). The gene span is 1,927 bases and the CCL2 gene resides on the Watson (plus) strand. The CCL2 gene … See more In humans, the levels of CCL2 can vary considerably. In the white people of European descent, the multivariable-adjusted heritability of CCL2 concentrations is … See more CCL2 is implicated in pathogeneses of several diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis and atherosclerosis. Administration of … See more • Yoshimura T, Leonard EJ (1991). "Human monocyte chemoattractant protein-1 (MCP-1)". Advances in Experimental Medicine and Biology. 305: 47–56. See more CCL2 is a monomeric polypeptide, with a molecular weight of approximately 13-15 kDa depending on levels of glycosylation. CCL2 is anchored in the plasma membrane of endothelial cells by glycosaminoglycan side chains of proteoglycans. … See more • Human CCL2 genome location and CCL2 gene details page in the UCSC Genome Browser. See more doctrine\u0027s jsWebApr 7, 2024 · For β-arrestin 2 recruitment, data shown are the mean ± SEM of BRET values 2–5 min following ligand stimulation; ... This indicates that structural changes induced in … doctrine\u0027s kaWebApr 7, 2024 · For β-arrestin 2 recruitment, data shown are the mean ± SEM of BRET values 2–5 min following ligand stimulation; ... This indicates that structural changes induced in β-arrestin 2 by the receptor and the type of chemokine ligand result in a significant positional change of the C domain with respect to the RLuc-fused N domain. Such observed ... dakine aero rack padsWebFeb 13, 2024 · Chemokine ligand-receptor interactions control leukocyte migration during inflammation, promoting migration from the circulation into the extravascular space in inflamed tissues (1, 2). Nearly 50 chemokines have been identified in mammals ( 3 ), commonly formed by four conserved cysteine residues—the first and third and the … dakine grindz food truck menu utahWebMar 6, 2024 · Chemokine receptors expressed by cancer cells promote their migration to metastatic sites ( 34 ). Chemokines and chemokine receptors involved in this phenomenon are several: CCR7 mediates the … doctrine\\u0027s zv